Description: Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.

Description: Dual specificity tyrosine-phosphorylation-regulated kinase 1A is an enzyme that in humans is encoded by the DYRK1A gene. This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.

Description: Additional name(s) for this target protein: Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human DYRK1A . This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody for detection of Dyrk1A from Human, Mouse, Rat. This Dyrk1A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Dyrk1A at AA range: 40-120

Description: A polyclonal antibody for detection of Dyrk1A from Human, Mouse, Rat. This Dyrk1A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Dyrk1A at AA range: 40-120

Description: A polyclonal antibody for detection of Dyrk1A from Human, Mouse, Rat. This Dyrk1A antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Dyrk1A at AA range: 40-120

Description: A Rabbit Polyclonal antibody against Dyrk1A from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Description: A Rabbit Polyclonal antibody against Dyrk1A from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human DYRK1A (N-term). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DYRK1A (N-Term). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mouse Dyrk1a (C-term). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Dyrk1a - N-terminal region. This antibody is tested and proven to work in the following applications: