Description: INCB024360 analog is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC
₅₀ of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). INCB024360 analog displays potential immunomodulating and antineoplastic activities.

Description: The 4x HDM Incomplete Assay Buffer does not contain
-ketoglutarate_x000D_and provides a more accurate background measure than using a no-enzyme control. It_x000D_has been optimized for use with the following BPS Bioscience histone demethylase_x000D_assay kits:_x000D_• FBXL10 (KDM2B) Homogeneous Assay Kit, BPS Cat. #50610_x000D_• FBXL11 (KDM2A) Homogeneous Assay Kit, BPS Cat. #50611_x000D_• JARID1A (KDM5A) Homogeneous Assay Kit, BPS Cat. #50510_x000D_• JARID1B (KDM5B) Homogeneous Assay Kit, BPS Cat. #50512_x000D_• JARID1C (KDM5C) Homogeneous Assay Kit, BPS Cat. #50511_x000D_• JHDM1D (KDM7A) Homogeneous Assay Kit, BPS Cat. #50420_x000D_• JMJD1A (KDM3A) Homogeneous Assay Kit, BPS Cat. #50412_x000D_• JMJD2A (KDM3A) Homogeneous Assay Kit, BPS Cat. #50413_x000D_• JMJD2B (KDM4B) Homogeneous Assay Kit, BPS Cat. #50414_x000D_• JMJD2C (KDM4C) Homogeneous Assay Kit, BPS Cat. #50415_x000D_• JMJD2E (KDM4DL) Homogeneous Assay Kit, BPS Cat. #50417_x000D_• JMJD3 (KDM6B) Homogeneous Assay Kit, BPS Cat. #50416_x000D_• PHF8 (KDM7B) Homogeneous Assay Kit, BPS Cat. #50515_x000D_• UTX (KDM6A) Homogeneous Assay Kit, BPS Cat. #50516

Description: Epacadostat (INCB024360) is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC₅₀
 of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Epacadostat displays potential immunomodulating and antineoplastic activities.

Description: Epacadostat (INCB024360) is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC₅₀
 of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Epacadostat displays potential immunomodulating and antineoplastic activities.

Description: Histone H3 Peptide, biotin conjugated. The peptide corresponds to residues 21-44 of histone H3.

Description: Histone H3 Peptide, a.a. 1-21, biotin conjugated. This sequence corresponds to the first 21 amino acids of the NH2 terminal of histone H3 followed by a GG linker and a biotinylated lysine.

Description: Histone H4 peptide, amino acids 1 to 21, acetylated at the N-terminus and biotinylated on the side chain of Lys. A GG spacer has been added on the C-terminus of Lys.

Description: Histone H4 peptide, amino acids 1 to 21, acetylated at the N-terminus and biotinylated on the side chain of Lys. A GG spacer has been added on the C-terminus of Lys.

Description: Biotinylation reagent with a pentafluorophenyl ester group. More reactive than the NHS ester group, targeting both primary and secondary amines. Suitable for biotin labeling of both proteins and amino acids.

Description: Biotinylation reagent with short 2 PEG spacer. Has a carboxyl group with a free -OH that can react with activated surfaces or can be converted to another reactive functionality.

Description: Biotinylation reagent with short 2 PEG spacer. Has a carboxyl group with a free -OH that can react with activated surfaces or can be converted to another reactive functionality.

Description: Biotinylation reagent with 3 PEG spacer. Has a carboxyl group with a free -OH that can react with activated surfaces or can be converted to another reactive functionality.