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Autoantibodies are major predictors of arthritis development in patients with anti-citrullinated protein antibodies and musculoskeletal pain

Aims: Predictors of arthritis improvement are extremely warranted amongst sufferers with anti-citrullinated protein antibodies (ACPAs) and musculoskeletal signs to optimize scientific administration. We aimed to establish scientific and laboratory predictors of arthritis improvement, together with biochemically assessed alcohol consumption, amongst ACPA-positive sufferers with musculoskeletal ache.

Methodology: 82 ACPA-positive people with musculoskeletal ache however no scientific arthritis had been adopted for a median of 72 months (interquartile vary 57-81 months). We evaluated the prognostic worth of baseline scientific and laboratory components together with smoking, symptom period, age, gender, shared epitope, rheumatoid issue (RF), anti-carbamylated protein antibodies, ACPA ranges, erythrocyte sedimentation fee, C-reactive protein ranges, tender joint depend, patient-reported common well-being, 28-joint Illness Exercise Rating, and alcohol consumption as measured by phosphatidyl ethanol (PEth) ranges in complete blood.

Outcomes: Throughout follow-up, 48% developed not less than one arthritis. Multivariable evaluation revealed an elevated danger of arthritis improvement with RF positivity and better ACPA ranges. Excessive ranges of RF entailed the best HR on this ACPA-positive inhabitants. Neither scientific traits nor alcohol consumption measured by PEth conferred vital prognostic worth.

Conclusions: ACPA ranges and concurrent presence of RF are impartial predictors of arthritis improvement amongst ACPA-positive sufferers with musculoskeletal ache. The outcomes are suitable with a dose-response relationship between RA-related autoantibodies and danger of arthritis improvement.

 

[Identifying protein epitopes recognized by monoclonal antibodies]

To determine a way for figuring out protein epitopes acknowledged by therapeutic monoclonal antibodies, the programmed demise receptor-1 (PD-1) was chosen because the goal protein. Primarily based on the alanine scanning technique, a fast expression methodology of antigen mutants combining site-directed mutagenesis with mammalian cell expression system was established, the situations for eukaryotic expression ingredient amplification and cell transfection expression had been established. 150 PD-1 protein mutants had been co-expressed, and the binding capability of those mutants to anti-PD-1 antibody Pembrolizumab was recognized.
The epitopes of Pembrolizumab had been decided based mostly on the binding capability of protein mutants to antibodies and mixed with protein construction evaluation, which was extremely in keeping with the reported crystal structure-based epitopes, indicating that this methodology is straightforward and correct and can be utilized for epitope mapping of therapeutic monoclonal antibodies. Therapeutic antibody medicine have achieved nice success in scientific apply. Nonetheless, their efficacy and security nonetheless have to be improved. On the identical time, extreme focus of drug targets will trigger issues resembling repeated improvement and waste of sources. Subsequently, pharmaceutical corporations have to discover differentiated discovery methods when researching antibody medicine so as to survive and develop within the fierce market competitors.
On this paper, the differential improvement technique of therapeutic antibody medicine is mentioned from the features of drug sources and codecs, drug goal choice, drug mechanism and differential drug traits. The continuing coronavirus illness 2019 (COVID-19) pandemic is a world public well being disaster, inflicting social and financial disasters in lots of nations. In China, two-consecutive destructive outcomes of nucleic acid assessments for SARS-CoV-2 from the respiratory samples are required to finish the quarantine of COVID-19 sufferers. Nonetheless, clinicians face a dilemma in case of sufferers with long-term viral shedding. This report described an uncommon COVID-19 case who had persistent viral RNA positivity for greater than four months after preliminary sickness within the presence of low neutralizing antibodies, however with out extended scientific signs. A number of anti-viral drug remedies had no affect and there was no proof of re-infection. When the affected person was self-quarantined at house, no an infection occurred to the three relations residing together with her for 15 to 19 days.
 Autoantibodies are major predictors of arthritis development in patients with anti-citrullinated protein antibodies and musculoskeletal pain
Autoantibodies are major predictors of arthritis development in patients with anti-citrullinated protein antibodies and musculoskeletal pain

Growth and biochemical characterization of the monoclonal antibodies for particular detection of the rising H5N8 and H5Nx avian influenza virus hemagglutinins

The extremely pathogenic avian influenza (HPAI) H5N8 virus has been detected in wild birds and poultry worldwide. The menace attributable to HPAI H5N8 virus nonetheless exists with considerations for human an infection. The preparedness for epidemic prevention and lowering the agricultural and financial misplaced is extraordinarily vital. Hemagglutinin (HA), a floor glycoprotein of influenza viruses, is taken into account as the foremost goal for detection of the influenza virus subtype within the contaminated samples.
On this examine, the recombinant H5N8 HA1 and HA2 proteins had been expressed in Escherichia coli, and had been utilized to generate two monoclonal antibodies, named 7H6C and YC8. 7H6C can bind the HA proteins of H5N1 and H5N8, however can not bind the HA proteins of H1N1, H3N2, and H7N9, indicating that it has H5-subtype specificity. In distinction, YC8 can bind the HA proteins of H1N1, H5N1, and H5N8, however can not bind the HA proteins of H3N2 and H7N9, indicating that it has H1-subtype and H5-subtype specificity. The epitope sequences acknowledged by 7H6C are situated within the head area of H5N8 HA, and are extremely conserved in H5 subtypes. The epitope sequences acknowledged by YC8 are situated within the stalk area of H5N8 HA, and are extremely conserved among the many H1 and H5 subtypes. 7H6C and YC8 could be utilized for particular detection of the HA proteins of H5N8 and H5Nx avian influenza viruses.

Eotaxin-2

ant-127 0.5mg
EUR 275
Description: Mouse Anti Human Eotaxin-2

Human Eotaxin-2 ELISA Kit

NSL0640Hu 96 wells
EUR 468

Eotaxin-2 (Human) ELISA Kit

EKA52020-5x96T 5x96T Ask for price

Eotaxin-2 (Human) ELISA Kit

EKA52020-96T 96T
EUR 446.9

Human Eotaxin 1 (Eotaxin 1/CCL11)ELISA Kit

GA-E0032HM-48T 48T
EUR 346.8

Human Eotaxin 1 (Eotaxin 1/CCL11)ELISA Kit

GA-E0032HM-96T 96T
EUR 559.2

Human Eotaxin 1 (Eotaxin 1/CCL11)ELISA Kit

QY-E01510 96T
EUR 433.2

Eotaxin 2

chm-238 5µg
EUR 60
Description: Recombinant Human Eotaxin-2 (CCL24)

Eotaxin-2 Antibody

20-abx137034
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Human Eotaxin 2 ELISA kit

E01E0165-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Eotaxin 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 2 ELISA kit

E01E0165-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Eotaxin 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 2 ELISA kit

E01E0165-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Eotaxin 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 2 ELISA Kit

EHE0172 96Tests
EUR 625.2

Mouse Eotaxin 2(Eotaxin 2/CCL24)ELISA Kit

GA-E0263MS-48T 48T
EUR 403.2

Mouse Eotaxin 2(Eotaxin 2/CCL24)ELISA Kit

GA-E0263MS-96T 96T
EUR 640.8

Recombinant Human Eotaxin-2 (CCL24)

7-01831 5µg Ask for price

Recombinant Human Eotaxin-2 (CCL24)

7-01832 20µg Ask for price

Recombinant Human Eotaxin-2 (CCL24)

7-01833 1mg Ask for price

Human Eotaxin-3 Antibody

32586-05111 150 ug
EUR 313.2

Eotaxin-2/CCL24, human recombinant

4497-1000 each
EUR 4431.6

Eotaxin-2/CCL24, human recombinant

4497-20 each
EUR 307.2

Eotaxin 2 antibody

10R-7737 500 ug
EUR 678
Description: Mouse monoclonal Eotaxin 2 antibody

Eotaxin 2 antibody

10R-E130A 500 ug
EUR 327.6
Description: Mouse monoclonal Eotaxin 2 antibody

Eotaxin 2 antibody

70R-EG005 50 ug
EUR 327.6
Description: Affinity purified Goat polyclonal Eotaxin 2 antibody

Eotaxin 2 antibody

70R-EG008 50 ug
EUR 327.6
Description: Affinity purified Goat polyclonal Eotaxin 2 antibody

Human Eotaxin-2/CCL24 ELISA KIT

E42EH-290 96T/48T Ask for price

anti- Eotaxin antibody

FNab02791 100µg
EUR 606.3
Description: Antibody raised against Eotaxin

Human CCL24/Eotaxin-2 ELISA Kit

E16HE0224 96T
EUR 833.33

Human Eotaxin (CCL11)

1-CSB-EP004775HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Eotaxin(CCL11) expressed in E.coli

Eotaxin/CCL11, Human

HY-P7159 50ug
EUR 555.6

Eotaxin, CCL11, human

RC315-22 5ug
EUR 125.26

Human Eotaxin-1 (CCL11 )

90127-A 5 µg
EUR 130
Description: Recombinant Eotaxin-1 is a disulfide-linked homodimeric protein consisting of 75 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Eotaxin-1 mature chain was expressed in E. coli.

Human Eotaxin-1 (CCL11 )

90127-B 20 µg
EUR 205
Description: Recombinant Eotaxin-1 is a disulfide-linked homodimeric protein consisting of 75 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Eotaxin-1 mature chain was expressed in E. coli.

Human Eotaxin-3(CCL26)

90129-A 5 µg
EUR 130
Description: Recombinant Eotaxin-3 is a disulfide-linked homodimeric protein consisting of 72 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Eotaxin-3 mature chain was expressed in E. coli.

Human Eotaxin-3(CCL26)

90129-B 20 µg
EUR 205
Description: Recombinant Eotaxin-3 is a disulfide-linked homodimeric protein consisting of 72 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Eotaxin-3 mature chain was expressed in E. coli.

Human Eotaxin 2/CCL24 ELISA Kit

201-12-0059 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Eotaxin 2/CCL24 ELISA Kit

CSB-E10360h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Eotaxin 2/CCL24 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Eotaxin 2/CCL24 ELISA Kit

1-CSB-E10360h
  • EUR 661.20
  • EUR 4584.00
  • EUR 2445.60
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Eotaxin 2/CCL24 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Eotaxin 2/CCL24 ELISA Kit

CN-03475H1 96T
EUR 549.6

Human Eotaxin 2/CCL24 ELISA Kit

CN-03475H2 48T
EUR 368.4

Human Eotaxin 2/CCL24 ELISA Kit

GA-E0098HM-48T 48T
EUR 346.8

Human Eotaxin 2/CCL24 ELISA Kit

GA-E0098HM-96T 96T
EUR 559.2

Human Eotaxin 2/CCL24 ELISA Kit

QY-E01509 96T
EUR 433.2

Human Eotaxin 2/CCL24 ELISA Kit

EKC31214-48T 48T
EUR 370.44

Human Eotaxin 2/CCL24 ELISA Kit

EKC31214-5x96T 5x96T
EUR 2513.7

Human Eotaxin 2/CCL24 ELISA Kit

EKC31214-96T 96T
EUR 529.2

Human Eotaxin-2 / MPIF-2 (CCL24) ELISA Kit

20-abx152374
  • EUR 6618.00
  • EUR 3536.40
  • EUR 830.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Eotaxin-3/CCL26, Human

HY-P7163 50ug
EUR 639.6

Eotaxin-3, CCL26, human

RC315-37 5ug
EUR 121.6

Recombinant Human Eotaxin-2/CCL24(CCL24)

HECCP-2401 5ug Ask for price

Recombinant Human Eotaxin-2 (CCL24) Protein

PROTO00175-1 20ug
EUR 380.4
Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

Eotaxin 2 protein

30R-2617 20 ug
EUR 362.4
Description: Purified recombinant Human Eotaxin 2 protein

Eotaxin 2 protein

30R-AE020 20 ug
EUR 327.6
Description: Purified recombinant Human Eotaxin 2 protein

Eotaxin-2 Polyclonal Antibody

46839-100ul 100ul
EUR 302.4

Eotaxin-2 Polyclonal Antibody

46839-50ul 50ul
EUR 224.4

Eotaxin-2 Polyclonal Antibody

ABP58486-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Eotaxin-2 from Human. This Eotaxin-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Eotaxin-2 protein at amino acid sequence of 61-110

Eotaxin-2 Polyclonal Antibody

ABP58486-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Eotaxin-2 from Human. This Eotaxin-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Eotaxin-2 protein at amino acid sequence of 61-110

Eotaxin-2 Polyclonal Antibody

ABP58486-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Eotaxin-2 from Human. This Eotaxin-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Eotaxin-2 protein at amino acid sequence of 61-110

Eotaxin-2 Polyclonal Antibody

ES8716-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Eotaxin-2 from Human. This antibody is tested and validated for IHC, WB, ELISA

Eotaxin-2 Polyclonal Antibody

ES8716-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Eotaxin-2 from Human. This antibody is tested and validated for IHC, WB, ELISA

Eotaxin-2 Polyclonal Antibody

E046839 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Eotaxin-2 Polyclonal Antibody

E11-2035959 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Human Eotaxin ELISA Kit

55R-1567 1 kit
EUR 636
Description: ELISA kit for detection of Eotaxin in the research laboratory

Human Eotaxin ELISA kit

LF-EK50029 1×96T
EUR 777.6

Human Eotaxin ELISA Kit

NSL0641Hu 96 wells
EUR 468

Eotaxin-2/CCL24, Rat

HY-P7162 10ug
EUR 280.8

Eotaxin-2, CCL24, rat

RC355-35 5ug
EUR 125.26

Eotaxin-2 Human Recombinant Protein (CCL24)

PROTO00175 Regular: 20ug
EUR 380.4
Description: CCL24 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 78 amino acids and having a molecular mass of 8.8 kDa. ;The CCL24 is purified by proprietary chromatographic techniques.

Goat anti-human Eotaxin antibody

70-1091 50 ug
EUR 360
Description: Purified Goat anti-human Eotaxin polyclonal antibody

Human eotaxin-3 ELISA Kit

SL3600Hu 96 Tests
EUR 468

Human Eotaxin 2 / MPIF-2 (CCL24) ELISA Kit

abx250202-96tests 96 tests
EUR 904.8

Human Eotaxin 2 / MPIF-2 (CCL24) ELISA Kit

abx513745-96tests 96 tests
EUR 904.8

Eotaxin-2 Rabbit pAb

E2252001 100ul
EUR 225
Description: Available in various conjugation types.

ELISA kit for Human Eotaxin 2/CCL24

EK0200 96 tests
EUR 794.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Eotaxin 2/CCL24 in samples from serum, plasma, tissue homogenates and other biological fluids.

Eotaxin (Human) ELISA Kit

EKA51830-5x96T 5x96T Ask for price

Eotaxin (Human) ELISA Kit

EKA51830-96T 96T
EUR 446.9

Eotaxin

chm-256 5µg
EUR 60
Description: Recombinant Human Eotaxin (CCL11)

Human CCL24/Eotaxin-2 PicoKine ELISA Kit

EK0331 96 wells
EUR 510
Description: For quantitative detection of human CCL24 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Eotaxin-3 (Human) ELISA Kit

EKA51831-5x96T 5x96T Ask for price

Eotaxin-3 (Human) ELISA Kit

EKA51831-96T 96T
EUR 446.9

Human Eotaxin-2 Recombinant Protein Lyophilized

IHUEOTXN2RLY5UG each
EUR 341
Description: Human Eotaxin-2 Recombinant Protein Lyophilized

Eotaxin-2 (CCL24) Protein

20-abx261546
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Eotaxin-2 (CCL24) Protein

20-abx261567
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Eotaxin 1/ Rat Eotaxin 1 ELISA Kit

ELA-E0026r 96 Tests
EUR 1063.2

Human Eotaxin 1 ELISA Kit

201-12-0113 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Eotaxin 1 ELISA Kit

CN-03168H1 96T
EUR 592.8

Human Eotaxin 1 ELISA Kit

CN-03168H2 48T
EUR 412.8

Human Eotaxin 1 ELISA kit

E01E0364-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Eotaxin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 1 ELISA kit

E01E0364-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Eotaxin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 1 ELISA kit

E01E0364-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Eotaxin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 3 ELISA kit

E01E0514-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Eotaxin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 3 ELISA kit

E01E0514-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Eotaxin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 3 ELISA kit

E01E0514-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Eotaxin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Eotaxin 1 ELISA Kit

EHE0171 96Tests
EUR 625.2

Human Eotaxin 1 ELISA Kit

EHE0371 96Tests
EUR 625.2

Human Eotaxin 1 ELISA Kit

SL0662Hu 96 Tests
EUR 468

Eotaxin-1

ant-126 0.5mg
EUR 275
Description: Mouse Anti Human Eotaxin-1 (CCL11)

Eotaxin Antibody

abx232791-100ug 100 ug
EUR 577.2

Eotaxin antibody

10R-E129A 500 ug
EUR 327.6
Description: Mouse monoclonal Eotaxin antibody

Eotaxin Antibody

1123-002mg 0.02 mg
EUR 206.18
Description: Eotaxin Antibody: Chemokines play a key role in inflammation. The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions. Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells. The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1.

Eotaxin Antibody

1123-01mg 0.1 mg
EUR 523.7
Description: Eotaxin Antibody: Chemokines play a key role in inflammation. The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions. Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells. The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1.

Eotaxin Antibody

24014-100ul 100ul
EUR 468

Eotaxin antibody

20R-1774 100 ug
EUR 807.6
Description: Rabbit polyclonal Eotaxin antibody

eotaxin Antibody

abx432653-200ul 200 ul
EUR 343.2

Eotaxin antibody

70R-12250 100 ug
EUR 536.4
Description: Rabbit polyclonal Eotaxin antibody

Eotaxin Antibody

R30607 100 ug
EUR 356.15
Description: Eotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.

Eotaxin Antibody

R31494 100 ug
EUR 356.15
Description: CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11/Eotaxin is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor.

ELISA kit for Human Eotaxin

EK1059 96 tests
EUR 542.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Eotaxin in samples from serum, plasma, tissue homogenates and other biological fluids.

Rat Eotaxin-2 ELISA Kit

NSL0580r 96 Tests
EUR 498

Recombinant Human Eotaxin (CCL11)

7-01819 5µg Ask for price

Recombinant Human Eotaxin (CCL11)

7-01820 20µg Ask for price

Recombinant Human Eotaxin (CCL11)

7-01821 1mg Ask for price

Recombinant Human Eotaxin(CCL11)

HECCP-1101 5ug Ask for price

Eotaxin-2 ELISA Kit (Human) : 96 Wells (OKAG00204)

OKAG00204 96 Wells
EUR 715.2
Description: Description of target: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 32 pg/mL

Recombinant Human Eotaxin-3 (CCL26)

7-01837 10µg Ask for price

Recombinant Human Eotaxin-3 (CCL26)

7-01838 50µg Ask for price

Recombinant Human Eotaxin-3 (CCL26)

7-01839 1mg Ask for price

Recombinant Human Eotaxin-3 (CCL26)

HECCP-2601 5ug Ask for price

Eotaxin 2 / MPIF-2 (CCL24) Antibody

abx411726-01mg 0.1 mg
EUR 844.8

Eotaxin 2 / MPIF-2 (CCL24) Antibody

abx411799-01mg 0.1 mg
EUR 727.2

Goat Eotaxin-2 ELISA Kit

NSL0792Gt 96T
EUR 528

Eotaxin-2 Recombinant Protein

40-349-0005mg 0.005 mg
EUR 311.1
Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3 kDa protein containing 93 amino acid residues.

Eotaxin-2 Recombinant Protein

40-349-002mg 0.02 mg
EUR 437.1
Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3 kDa protein containing 93 amino acid residues.

Eotaxin-2 Recombinant Protein

40-384-0005mg 0.005 mg
EUR 311.1
Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

Eotaxin-2 Recombinant Protein

40-384-002mg 0.02 mg
EUR 437.1
Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

Eotaxin 2 protein (Mouse)

30R-AE021 20 ug
EUR 327.6
Description: Purified recombinant Mouse Eotaxin 2 protein

Human Eotaxin-3 Antibody (Biotin Conjugate)

32586-05121 150 ug
EUR 442.8

Human Eotaxin-3/CCL26 ELISA KIT

E42EH-292 96T/48T Ask for price

Human Eotaxin-3/CCL26  ELISA Kit

NSL2113Hu 96 wells
EUR 468

Human Eotaxin (CCL11) ELISA Kit

20-abx151374
  • EUR 6768.00
  • EUR 3610.80
  • EUR 848.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Eotaxin (CCL11) ELISA Kit

abx250465-96tests 96 tests
EUR 801.6

Human Eotaxin (CCL11) ELISA Kit

abx050060-96tests 96 tests
EUR 801.6

Human Eotaxin (CCL11) ELISA Kit

abx350546-96tests 96 tests
EUR 801.6

Human Eotaxin ELISA kit (4X96T)

LF-EK50030 4×96T
EUR 2641.2

Human Eotaxin (CCL10) ELISA Kit

IHUCCL11KT each
EUR 702
Description: Human Eotaxin (CCL10) ELISA Kit

Human Eotaxin (CCL11) ELISA Kit

RK10020 96T
EUR 280

Goat Anti Mouse Eotaxin 2 Polyclonal Antibody

CPBT-65132GM 0.1 mg
EUR 1057.2

Eotaxin/CCL11, human recombinant

4028-100 each
EUR 927.6

Eotaxin/CCL11, human recombinant

4028-1000 each
EUR 4300.8

Eotaxin/CCL11, human recombinant

4028-20 each
EUR 307.2

Eotaxin-3/CCL26, human recombinant

7138-10 each
EUR 248.4

Eotaxin-3/CCL26, human recombinant

7138-50 each
EUR 810
KEY POINTS: • The mAb 7H6C or YC8 was generated by utilizing the HA1 or HA2 of the HPAI H5N8 virus because the immunogen. • 7H6C acknowledged the top area of H5N8 HA, and YC8 acknowledged the stalk area of H5N8 HA. • 7H6C and YC8 can detect the HA proteins of H5Nx subtypes particularly.

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