P-glypoprotein Inhibition Effect on the Pharmacokinetics

P-glypoprotein Inhibition Impact on the Pharmacokinetics of Two Tacrolimus Formulations: Extended and Prolonged-release

Tacrolimus is a drug administered orally accessible with totally different formulations: speedy launch (Prograf®), prolonged-release (Advagraf®) and an extended-release one named LCP-Tacro (Envarsus®), formulated utilizing the Soften-Dose course of.

Tacrolimus is a lipophilic macrolide drug capable of passive transmembrane diffusion.

Its bioavailability shows a big interindividual variability, from 9 to 43%.

Certainly, tacrolimus is a substrate of P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4).

P-gp is an efflux protein primarily positioned on the apex of the epithelia of the gut, lymphocyte, kidney and blood-brain barrier. P-gp due to this fact limits the intestinal resorption of tacrolimus and likewise its diffusion into its goal compartment (i.e the lymphocyte.

The expression of this protein is totally different all through the digestive tract with most expression on the ileal stage.

CYP3A4 is a coenzyme that’s accountable of greater than 90% of the metabolism of tacrolimus, on the digestive and hepatic stage. Each P-gp and CYP3A4 play a job in tacrolimus absorption/diffusion course of.

A brand new formulation of tacrolimus, LCP-Tacro, (Envarsus®) was accepted in 2014. Its efficacy was in comparison with Prograf® in two section III de novo or swap Prograf® trials in kidney transplantation.

With tacrolimus, there’s a robust inter-individual pharmacokinetic variability which, up to now, has not been totally characterised. Variations in bioavailability could partly clarify this excessive variability.

The totally different formulations are resorbed at distinct gastrointestinal websites which may clarify totally different absorptions between Prograf/Advagraf and LCP-Tacro varieties.

These findings elevate the query of the function of P-gp in explaining the distinction in bioavailability between formulations. The usage of a P-gp inhibitor may due to this fact have a distinct affect on publicity to totally different galenic formulations.

Verapamil is an inhibitor of P-gp and CYP 3A4, which is ceaselessly prescribed and advisable by FDA for drug-drug interplay research aiming at evaluating P-gp substrates, utilized in healthyvolunteers at dosages as much as 240 mg/D13-14. In any other case, verapamil-tacrolimusinteraction has been characterised in vitro.

It has additionally been proven that inhibitory impact of verapamil at a single dose of 120mg administered one hour previous to the administration of a P-gp substrate exhibited an optimum energy of inhibition.

The protection of Advagraf® and Envarsus® administrations have already been subjected to a number of section I trials in wholesome volunteers reinforcing the data of their security profile.

The purpose of the examine is to match the interplay profile of Advagraf® and Envarsus® when co-administered with verapamil in wholesome topics and to supply pointers on tacrolimus dosage adjustment in such circumstances.

cd-34
cd-34

Anti-Podoplanin Antibody

A1564-100
EUR 479

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Podoplanin

MO47016 100 ul
EUR 349

Anti-Podoplanin Rabbit Monoclonal Antibody

M01124-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Podoplanin Rabbit Monoclonal Antibody

M01124-2 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human.

Anti-Podoplanin/gp36/PDPN Antibody

PA1411 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody

PA1674 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody

PA1675 100ug/vial
EUR 294

Anti-D2-40 Podoplanin antibody

STJ16100360 1 mL
EUR 1235

Anti-D2-40/Podoplanin antibody

STJ190048 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1)

Anti-Podoplanin/gp36/PDPN Antibody

A01124 100ug/vial
EUR 294

Mouse Podoplanin (PDPN) Protein

20-abx650139
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Podoplanin ELISA kit

E03P0082-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit

E03P0082-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit

E03P0082-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761

CABT-L2919-100uL500uL 100 uL, 500 uL
EUR 502

Podoplanin Antibody

49474-100ul 100ul
EUR 333

Podoplanin Antibody

49474-50ul 50ul
EUR 239

Podoplanin Antibody

P1051-01m 0.1m
EUR 209

Podoplanin Antibody

P1051-1ml 1ml
EUR 941

Podoplanin Antibody

DF12456 200ul
EUR 304
Description: Podoplanin antibody detects endogenous levels of Podoplanin.

Podoplanin antibody

10R-7662 100 ug
EUR 629
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody

10R-7663 100 ug
EUR 629
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody

10R-7664 100 ug
EUR 629
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody

10R-P133a 100 ug
EUR 507
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody

10R-P155a 100 ug
EUR 543
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody

70R-11540 100 ug
EUR 527
Description: Rabbit polyclonal Podoplanin antibody

Podoplanin antibody

70R-13952 100 ug
EUR 305
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody

70R-6816 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN

Podoplanin antibody

70R-6817 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN

Podoplanin antibody

70R-50819 100 ul
EUR 244
Description: Purified Polyclonal Podoplanin antibody

Podoplanin antibody

70R-PR007 100 ug
EUR 422
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Podoplanin (PDPN) Polyclonal Antibody (Mouse)

4-PAC719Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN)

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-1x48wellstestplate 1x48-wells test plate
EUR 488.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-1x96wellstestplate 1x96-wells test plate
EUR 654.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

SEC719Mu-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

4-SEC719Mu
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Podoplanin (PDPN) ELISA Kit

RD-PDPN-Mu-48Tests 48 Tests
EUR 533

Mouse Podoplanin (PDPN) ELISA Kit

RD-PDPN-Mu-96Tests 96 Tests
EUR 740

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu-48T 48T
EUR 527
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu-96T 96T
EUR 688
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

abx571749-96tests 96 tests
EUR 786

Mouse Podoplanin (PDPN) CLIA Kit

20-abx493858
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Podoplanin (PDPN) ELISA Kit

20-abx154564
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Podoplanin (PDPN) ELISA Kit

RDR-PDPN-Mu-48Tests 48 Tests
EUR 557

Mouse Podoplanin (PDPN) ELISA Kit

RDR-PDPN-Mu-96Tests 96 Tests
EUR 774

Mouse Podoplanin(PDPN)ELISA kit

QY-E21215 96T
EUR 361

Recombinant Mouse Podoplanin (C-Fc)

CU73-10ug 10ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)

CU73-1mg 1mg
EUR 1674
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)

CU73-500ug 500ug
EUR 1166
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)

CU73-50ug 50ug
EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Mouse Podoplanin, Pdpn ELISA KIT

ELI-06723m 96 Tests
EUR 865

Recombinant Podoplanin (PDPN)

4-RPC719Hu01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Podoplanin expressed in: E.coli

Recombinant Podoplanin (PDPN)

4-RPC719Mu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Podoplanin expressed in: E.coli

Podoplanin (PDPN) Antibody

20-abx129101
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Podoplanin (PDPN) Antibody

20-abx131102
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Podoplanin (PDPN) Antibody

20-abx114559
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Podoplanin (PDPN) Antibody

20-abx123399
  • EUR 592.00
  • EUR 857.00
  • EUR 411.00
  • 100 ul
  • 200 ul
  • 50 ul

Podoplanin (PDPN) Antibody

20-abx339428
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Podoplanin Blocking Peptide

20-abx063694
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Recombinant Human Podoplanin

7-05839 5µg Ask for price

Recombinant Human Podoplanin

7-05840 25µg Ask for price

Recombinant Human Podoplanin

7-05841 1mg Ask for price

Podoplanin (PDPN) Antibody

20-abx137407
  • EUR 704.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 20 ug
  • 5 ug

Podoplanin (PDPN) Antibody

20-abx005408
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Podoplanin (PDPN) Antibody

20-abx008317
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Podoplanin (PDPN) Antibody

abx433110-200ul 200 ul
EUR 384

Podoplanin (PDPN) Protein

20-abx262003
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

Podoplanin (PDPN) Antibody

abx236598-100ug 100 ug
EUR 551

Podoplanin (PDPN) Antibody

abx236599-100ug 100 ug
EUR 551

Podoplanin (PDPN) Antibody

20-abx211099
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Podoplanin (PDPN) Antibody

20-abx178065
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Podoplanin (PDPN) Antibody

20-abx178066
  • EUR 1302.00
  • EUR 620.00
  • 1 mg
  • 200 ug

Podoplanin (PDPN) Antibody

20-abx178067
  • EUR 1414.00
  • EUR 662.00
  • 1 mg
  • 200 ug

Podoplanin (PDPN) Antibody

20-abx174125
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Podoplanin (PDPN) Antibody

20-abx174126
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Podoplanin Conjugated Antibody

C49474 100ul
EUR 397

Podoplanin Blocking Peptide

DF12456-BP 1mg
EUR 195

Podoplanin Blocking Peptide

33R-9441 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PDPN antibody, catalog no. 70R-6817

Podoplanin Blocking Peptide

33R-2420 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PDPN antibody, catalog no. 70R-6816

Podoplanin Recombinant Protein

91-478 0.05 mg
EUR 448.25
Description: Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn’t have any effect on amino acid transport and the aquaporin-type water channels.

Podoplanin Recombinant Protein

91-788 0.05 mg
EUR 490.25
Description: Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn’t have any effect on amino acid transport and the aquaporin-type water channels.

 

Efficacy and Security of Tigerase® vs. Pulmozyme® in Sufferers With Cystic Fibrosis

Cystic fibrosis (CF) is a standard hereditary illness with an autosomal recessive sort of inheritance, characterised by systemic injury to the exocrine glands, primarily the bronchopulmonary and gastrointestinal methods.

CF is often characterised by a extreme course and poor prognosis.

The severity of the illness and the life expectancy of the affected person with CF is decided primarily by the state of the bronchopulmonary system; greater than 90% of sufferers die from lung illnesses.

CF Pulmonary injury develops as a consequence of a gene mutation – cystic fibrosis transmembrane regulator of ion conductivity Na and Cl (CFTR-cystic fibrosis transmembrane regulator).

The primary operate of CFTR is to manage the transport of sodium and chlorine throughout the cell membrane and is a part of the cAMP-dependent chlorine channel.

CFTR-protein dysfunction within the bronchial tree epithelial cells results in a blockage of the chlorine ions transport and a rise within the sodium ions absorption, and impaired fluid secretion by the epithelial cells apical membrane.

Dornase alpha, a human recombinant deoxyribonuclease 1 (rhDNase, rhDNase) hydrolyzes extracellular DNA (viscous polyanion) that enters the sputum from destroyed neutrophils, thereby decreasing the adhesion and viscosity of sputum.

In CF sufferers dornase alpha is used as symptomatictherapy together with normal remedy in sufferers with a pressured important capability (FVC) index of no less than 40% of the correct worth.

Human Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Hu-48Tests 48 Tests
EUR 522

Human Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Hu-96Tests 96 Tests
EUR 724

Anti-CD163

DB-045-0.1 100 μl
EUR 212
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-0.2 200 μl
EUR 298
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-0.5 500 μl
EUR 384
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-1 1 ml
EUR 613
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB-045-RTU-7 7 ml
EUR 231
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-7 7 ml
EUR 231
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Mu-48Tests 48 Tests
EUR 511

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Mu-96Tests 96 Tests
EUR 709

Rat Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Ra-48Tests 48 Tests
EUR 511

Rat Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Ra-96Tests 96 Tests
EUR 709

Mouse Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Mu-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Mu-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Ra-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Ra-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Mu-48Tests 48 Tests
EUR 534

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Mu-96Tests 96 Tests
EUR 742

Rat Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Ra-48Tests 48 Tests
EUR 534

Rat Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Ra-96Tests 96 Tests
EUR 742

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-CD163 Antibody

PA1874 100ug/vial
EUR 294

Anti-CD163 Antibody

PA1874-1 100ug/vial
EUR 334

Anti-CD163 antibody

STJ160082 1 mL C
EUR 941

Anti-CD163 antibody

STJ16100302 100 µg
EUR 720

Anti-CD163 antibody

STJ16100324 1 mL
EUR 979

Anti-CD163 antibody

STJ180301 0.1 ml
EUR 215

Anti-CD163 antibody

STJ190009 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to CD163 (AS1A1)

Anti-CD163 Antibody

STJ500423 100 µg
EUR 476

Anti-CD163 Antibody

STJ500424 100 µg
EUR 476

Anti-CD163 antibody

STJ110681 100 µl
EUR 277
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Anti-CD163 Antibody

A00812-1 100ug/vial
EUR 334

Anti-CD163 Antibody BIOTIN

STJ500425 100 µg
EUR 586

Anti-CD163 Antibody FITC

STJ500426 100 µg
EUR 586

Anti-CD163 Antibody BIOTIN

STJ500427 100 µg
EUR 586

Anti-CD163 Antibody FITC

STJ500428 100 µg
EUR 586

Anti-CD163/M130 Antibody

A00812 100ul
EUR 397
Description: Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130 (CD163) detection.tested for IF, IHC, WB in Human, Mouse, Rat. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details.

Anti-Hu CD163 Purified

11-645-C025 0.025 mg
EUR 99

Anti-Hu CD163 Purified

11-645-C100 0.1 mg
EUR 158

Anti-Hu CD163 APC

1A-645-T025 25 tests
EUR 140

Anti-Hu CD163 APC

1A-645-T100 100 tests
EUR 240

Anti-Hu CD163 PE

1P-645-T025 25 tests
EUR 140

Anti-Hu CD163 PE

1P-645-T100 100 tests
EUR 240

anti- CD163/M130 Antibody

FNab09771 100µg
EUR 548.75
Description: Antibody raised against CD163/M130 

Anti-CD163/M130 antibody

PAab09771 100 ug
EUR 355

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-48T 48T
EUR 289

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-96T 96T
EUR 466

human CD163 antigen,CD163 LISA kit

201-12-0247 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human CD163 antigen(CD163)ISA kit

QY-E05066 96T
EUR 361

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47162MH 25 µg
EUR 372

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47163MH 0.2 mg
EUR 881

Anti-CD163 Rabbit Monoclonal Antibody

M00812 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD163 Antibody. Validated in IP, WB and tested in Human.

Anti-Hu CD163 PE-Cy7

T7-645-T025 25 tests
EUR 154

Anti-Hu CD163 PE-Cy7

T7-645-T100 100 tests
EUR 268

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T025 25 tests
EUR 196

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T100 100 tests
EUR 352

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-48T 48T
EUR 364

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-96T 96T
EUR 590

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-48T 48T
EUR 402

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-96T 96T
EUR 684

CD163 Antibody

1-CSB-PA969205
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody

1-CSB-PA801238LA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

Cd163 Antibody

1-CSB-PA650452LA01MO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 Antibody

37157-100ul 100ul
EUR 252

CD163 siRNA

20-abx910930
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD163 siRNA

20-abx910931
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD163 Antibody

20-abx242956
  • EUR 467.00
  • EUR 328.00
  • 100 ul
  • 50 ul

CD163 Antibody

49553-100ul 100ul
EUR 333

CD163 Antibody

49553-50ul 50ul
EUR 239

CD163 Antibody

ABD8235 100 ug
EUR 438

CD163 Antibody

DF8235 200ul
EUR 304
Description: CD163 Antibody detects endogenous levels of total CD163.

CD163 antibody

10R-6496 100 ug
EUR 203
Description: Mouse monoclonal CD163 antibody

CD163 antibody

10R-CD163aRT 250 ug
EUR 716
Description: Mouse monoclonal CD163 antibody

Mouse Anti Rat Cd163 Monoclonal Antibody

DMABT-47170MR 0.25 mg
EUR 741

Mouse Anti Rat Cd163 Monoclonal Antibody

DMABT-47171MR 0.1 mg
EUR 559

Anti-Human CD163 DyLight® 488 conjugated Antibody

A00812-Dyl488 100ug/vial
EUR 344

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