P-glypoprotein Inhibition Effect on the Pharmacokinetics
P-glypoprotein Inhibition Impact on the Pharmacokinetics of Two Tacrolimus Formulations: Extended and Prolonged-release
Tacrolimus is a drug administered orally accessible with totally different formulations: speedy launch (Prograf®), prolonged-release (Advagraf®) and an extended-release one named LCP-Tacro (Envarsus®), formulated utilizing the Soften-Dose course of.
Tacrolimus is a lipophilic macrolide drug capable of passive transmembrane diffusion.
Its bioavailability shows a big interindividual variability, from 9 to 43%.
Certainly, tacrolimus is a substrate of P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4).
P-gp is an efflux protein primarily positioned on the apex of the epithelia of the gut, lymphocyte, kidney and blood-brain barrier. P-gp due to this fact limits the intestinal resorption of tacrolimus and likewise its diffusion into its goal compartment (i.e the lymphocyte.
The expression of this protein is totally different all through the digestive tract with most expression on the ileal stage.
CYP3A4 is a coenzyme that’s accountable of greater than 90% of the metabolism of tacrolimus, on the digestive and hepatic stage. Each P-gp and CYP3A4 play a job in tacrolimus absorption/diffusion course of.
A brand new formulation of tacrolimus, LCP-Tacro, (Envarsus®) was accepted in 2014. Its efficacy was in comparison with Prograf® in two section III de novo or swap Prograf® trials in kidney transplantation.
With tacrolimus, there’s a robust inter-individual pharmacokinetic variability which, up to now, has not been totally characterised. Variations in bioavailability could partly clarify this excessive variability.
The totally different formulations are resorbed at distinct gastrointestinal websites which may clarify totally different absorptions between Prograf/Advagraf and LCP-Tacro varieties.
These findings elevate the query of the function of P-gp in explaining the distinction in bioavailability between formulations. The usage of a P-gp inhibitor may due to this fact have a distinct affect on publicity to totally different galenic formulations.
Verapamil is an inhibitor of P-gp and CYP 3A4, which is ceaselessly prescribed and advisable by FDA for drug-drug interplay research aiming at evaluating P-gp substrates, utilized in healthyvolunteers at dosages as much as 240 mg/D13-14. In any other case, verapamil-tacrolimusinteraction has been characterised in vitro.
It has additionally been proven that inhibitory impact of verapamil at a single dose of 120mg administered one hour previous to the administration of a P-gp substrate exhibited an optimum energy of inhibition.
The protection of Advagraf® and Envarsus® administrations have already been subjected to a number of section I trials in wholesome volunteers reinforcing the data of their security profile.
The purpose of the examine is to match the interplay profile of Advagraf® and Envarsus® when co-administered with verapamil in wholesome topics and to supply pointers on tacrolimus dosage adjustment in such circumstances.
Mouse Anti Human Podoplanin |
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MBS140296-5x01mg | MyBiosource | 5x0.1mg | EUR 2405 |
MOUSE ANTI HUMAN PODOPLANIN |
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MBS212743-01mg | MyBiosource | 0.1mg | EUR 450 |
MOUSE ANTI HUMAN PODOPLANIN |
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MBS212743-5x01mg | MyBiosource | 5x0.1mg | EUR 1840 |
Hamster anti Podoplanin (mouse) |
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103-M40 | Angio Proteomie | 100ug | EUR 297.6 |
Mouse Anti-Human Podoplanin |
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MBS690117-0025mg | MyBiosource | 0.025mg | EUR 310 |
Mouse Anti-Human Podoplanin |
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MBS690117-5x0025mg | MyBiosource | 5x0.025mg | EUR 1110 |
Mouse Anti-Human Podoplanin |
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MBS690586-01mg | MyBiosource | 0.1mg | EUR 450 |
Mouse Anti-Human Podoplanin |
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MBS690586-5x01mg | MyBiosource | 5x0.1mg | EUR 1725 |
Mouse Anti-Human Podoplanin |
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MBS690680-0025mg | MyBiosource | 0.025mg | EUR 310 |
Mouse Anti-Human Podoplanin |
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MBS690680-5x0025mg | MyBiosource | 5x0.025mg | EUR 1110 |
Mouse Anti-Human Podoplanin |
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MBS690759-01mg | MyBiosource | 0.1mg | EUR 450 |
Mouse Anti-Human Podoplanin |
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MBS690759-5x01mg | MyBiosource | 5x0.1mg | EUR 1725 |
Mouse Anti-Human Podoplanin |
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MBS690992-005mg | MyBiosource | 0.05mg | EUR 430 |
Mouse Anti-Human Podoplanin |
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MBS690992-5x005mg | MyBiosource | 5x0.05mg | EUR 1645 |
Mouse Anti-Human Podoplanin |
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MBS692357-005mg | MyBiosource | 0.05mg | EUR 450 |
Mouse Anti-Human Podoplanin |
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MBS692357-5x005mg | MyBiosource | 5x0.05mg | EUR 1725 |
Mouse Anti-Human Podoplanin |
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MBS692358-005mg | MyBiosource | 0.05mg | EUR 450 |
Mouse Anti-Human Podoplanin |
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MBS692358-5x005mg | MyBiosource | 5x0.05mg | EUR 1725 |
Mouse anti Podoplanin-Biotin (human) |
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101-MBi40 | Angio Proteomie | 50ug | EUR 297.6 |
Hamster anti Podoplanin-Biotin (mouse) |
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103-MBi40 | Angio Proteomie | 50ug | EUR 297.6 |
Podoplanin Mouse mAb |
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A18776 | Abclonal | 100μL | EUR 719.13 |
Mouse Anti Human Podoplanin clone P56F7AT |
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MBS146676-0005mg | MyBiosource | 0.005mg | EUR 240 |
Mouse Anti Human Podoplanin clone P56F7AT |
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MBS146676-002mg | MyBiosource | 0.02mg | EUR 310 |
Mouse Anti Human Podoplanin clone P56F7AT |
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MBS146676-01mg | MyBiosource | 0.1mg | EUR 610 |
Mouse Anti Human Podoplanin clone P56F7AT |
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MBS146676-5x01mg | MyBiosource | 5x0.1mg | EUR 2405 |
Mouse Podoplanin, soluble |
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MBS691731-0005mg | MyBiosource | 0.005mg | EUR 250 |
Mouse Podoplanin, soluble |
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MBS691731-5x0005mg | MyBiosource | 5x0.005mg | EUR 835 |
Anti-Human/Mouse PDPN/Podoplanin Antibody |
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MBS1569238-01mg | MyBiosource | 0.1mg | EUR 405 |
Anti-Human/Mouse PDPN/Podoplanin Antibody |
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MBS1569238-5x01mg | MyBiosource | 5x0.1mg | EUR 1520 |
Recombinant Mouse Podoplanin |
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MBS7610672-005mg | MyBiosource | 0.05mg | EUR 345 |
Recombinant Mouse Podoplanin |
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MBS7610672-02mg | MyBiosource | 0.2mg | EUR 635 |
Recombinant Mouse Podoplanin |
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MBS7610672-1mg | MyBiosource | 1mg | EUR 1800 |
Recombinant Mouse Podoplanin |
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MBS7610672-5x1mg | MyBiosource | 5x1mg | EUR 6955 |
Mouse Monoclonal anti-Rat Podoplanin Antibody |
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xAP-0897 | Angio Proteomie | 100ug | EUR 280 |
Mouse Podoplanin ELISA kit |
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E01A24381 | BlueGene | 96T | EUR 700 |
Description: ELISA |
Mouse Podoplanin ELISA kit |
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E03P0082-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA kit |
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E03P0082-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA kit |
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E03P0082-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA Kit |
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IMSPDPNKT | Innovative research | each | EUR 752 |
Description: Mouse Podoplanin ELISA Kit |
Mouse Podoplanin ELISA Kit |
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MBS725552-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Mouse Podoplanin ELISA Kit |
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MBS725552-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Mouse Podoplanin ELISA Kit |
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MBS725552-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Mouse Podoplanin ELISA Kit |
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MBS725552-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Mouse Podoplanin ELISA Kit |
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MBS2884556-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4080 |
Mouse Podoplanin ELISA Kit |
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MBS2884556-48StripWells | MyBiosource | 48-Strip-Wells | EUR 390 |
Mouse Podoplanin ELISA Kit |
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MBS2884556-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2220 |
Mouse Podoplanin ELISA Kit |
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MBS2884556-96StripWells | MyBiosource | 96-Strip-Wells | EUR 520 |
Hamster Anti-Mouse Podoplanin |
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MBS690646-01mg | MyBiosource | 0.1mg | EUR 450 |
Hamster Anti-Mouse Podoplanin |
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MBS690646-5x01mg | MyBiosource | 5x0.1mg | EUR 1725 |
Hamster Anti-Mouse Podoplanin |
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MBS690790-005mg | MyBiosource | 0.05mg | EUR 430 |
Hamster Anti-Mouse Podoplanin |
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MBS690790-5x005mg | MyBiosource | 5x0.05mg | EUR 1645 |
Anti-Mouse Podoplanin Antibody |
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103-M552 | ReliaTech | 100 µg | EUR 399 |
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Mouse Podoplanin Antibody |
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103-PA40 | ReliaTech | 200 µg | EUR 204.75 |
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Anti-Mouse Podoplanin Antibody |
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103-PA40S | ReliaTech | 100 µg | EUR 126 |
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. |
Mouse Podoplanin (PDPN) Protein |
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20-abx650139 | Abbexa |
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Mouse Podoplanin (PDPN) Protein |
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abx694266-10nmol | Abbexa | 10 nmol | EUR 700 |
Mouse Podoplanin (PDPN) Protein |
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abx694266-5nmol | Abbexa | 5 nmol | EUR 462.5 |
Mouse Podoplanin (PDPN) Protein |
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abx650139-100g | Abbexa | 100 µg | EUR 537.5 |
Mouse Podoplanin (PDPN) Protein |
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abx650139-10g | Abbexa | 10 µg | EUR 212.5 |
Mouse Podoplanin (PDPN) Protein |
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abx650139-50g | Abbexa | 50 µg | EUR 375 |
Podoplanin (ABT513) Mouse mAb |
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UB-GEN-14883 | UpingBio | 100 ul | EUR 200 |
Podoplanin (ABT360) Mouse mAb |
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UB-GEN-15155 | UpingBio | 100 ul | EUR 200 |
Mouse Monoclonal Podoplanin Antibody |
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TA327727 | Origene Technologies GmbH | 1 ml | Ask for price |
anti- Podoplanin antibody |
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FNab06598 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against Podoplanin |
anti- Podoplanin antibody |
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FNab06599 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against Podoplanin |
Mouse Podoplanin (PDPN) CLIA Kit |
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20-abx493858 | Abbexa |
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Mouse Podoplanin (PDPN) ELISA Kit |
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abx571749-96tests | Abbexa | 96 tests | EUR 943.2 |
Mouse Podoplanin (PDPN) ELISA Kit |
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20-abx154564 | Abbexa |
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Mouse Podoplanin (PDPN) ELISA Kit |
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DLR-PDPN-Mu | DL Develop | 96T | EUR 475 |
Description: tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
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DLR-PDPN-Mu-48T | DL Develop | 48T | EUR 632.4 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
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DLR-PDPN-Mu-96T | DL Develop | 96T | EUR 825.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
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DL-PDPN-Mu | DL Develop | 96T | EUR 453 |
Description: tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
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EK8596 | SAB | 96Т | EUR 799 |
Mouse Podoplanin (PDPN) ELISA Kit |
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EKN47838-48T | Biomatik Corporation | 48T | EUR 389.62 |
Mouse Podoplanin (PDPN) ELISA Kit |
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EKN47838-5x96T | Biomatik Corporation | 5x96T | EUR 2643.85 |
Mouse Podoplanin (PDPN) ELISA Kit |
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EKN47838-96T | Biomatik Corporation | 96T | EUR 556.6 |
Mouse Podoplanin (PDPN) ELISA Kit |
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AE28131MO-48Tests | Abebio | 48 Tests | EUR 325 |
Description: Mouse (Mus musculus) |
Mouse Podoplanin (PDPN) ELISA Kit |
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AE28131MO-96Tests | Abebio | 96 Tests | EUR 610 |
Description: Mouse (Mus musculus) |
Mouse Podoplanin (PDPN)ELISA kit |
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YLA0596MO-48T | Shanghai YL Biotech | 48T | Ask for price |
Mouse Podoplanin (PDPN)ELISA kit |
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YLA0596MO-96T | Shanghai YL Biotech | 96T | Ask for price |
Mouse Podoplanin, Pdpn ELISA KIT |
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ELI-06723m | Nova Lifetech | 96tests | EUR 736 |
Mouse Podoplanin,PDPN ELISA KIT |
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E1437Mo-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Mouse Podoplanin,PDPN ELISA KIT |
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E1437Mo-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Mouse Podoplanin,PDPN ELISA KIT |
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E1437Mo-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Mouse Podoplanin,PDPN ELISA KIT |
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E1437Mo-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Mouse Podoplanin (PDPN) ELISA Kit |
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EKU06727-48T | Biomatik Corporation | 48T | EUR 571.55 |
Efficacy and Security of Tigerase® vs. Pulmozyme® in Sufferers With Cystic Fibrosis
Cystic fibrosis (CF) is a standard hereditary illness with an autosomal recessive sort of inheritance, characterised by systemic injury to the exocrine glands, primarily the bronchopulmonary and gastrointestinal methods.
CF is often characterised by a extreme course and poor prognosis.
The severity of the illness and the life expectancy of the affected person with CF is decided primarily by the state of the bronchopulmonary system; greater than 90% of sufferers die from lung illnesses.
CF Pulmonary injury develops as a consequence of a gene mutation – cystic fibrosis transmembrane regulator of ion conductivity Na and Cl (CFTR-cystic fibrosis transmembrane regulator).
The primary operate of CFTR is to manage the transport of sodium and chlorine throughout the cell membrane and is a part of the cAMP-dependent chlorine channel.
CFTR-protein dysfunction within the bronchial tree epithelial cells results in a blockage of the chlorine ions transport and a rise within the sodium ions absorption, and impaired fluid secretion by the epithelial cells apical membrane.
Dornase alpha, a human recombinant deoxyribonuclease 1 (rhDNase, rhDNase) hydrolyzes extracellular DNA (viscous polyanion) that enters the sputum from destroyed neutrophils, thereby decreasing the adhesion and viscosity of sputum.
In CF sufferers dornase alpha is used as symptomatictherapy together with normal remedy in sufferers with a pressured important capability (FVC) index of no less than 40% of the correct worth.
human anti-human CD163 mAb |
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E4A09C49 | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Mouse Anti Human CD163: RPE |
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MBS225636-100Tests | MyBiosource | 100Tests | EUR 520 |
Mouse Anti Human CD163: RPE |
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MBS225636-5x100Tests | MyBiosource | 5x100Tests | EUR 2160 |
MOUSE ANTI HUMAN CD163: FITC |
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MBS225948-01mg | MyBiosource | 0.1mg | EUR 435 |
MOUSE ANTI HUMAN CD163: FITC |
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MBS225948-5x01mg | MyBiosource | 5x0.1mg | EUR 1785 |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-48Tests | GenAsia Biotech | 48 Tests | Ask for price |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-96Tests | GenAsia Biotech | 96 Tests | EUR 388 |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human CD163 antigen(CD163)ISA kit |
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QY-E05066 | Qayee Biotechnology | 96T | EUR 433.2 |
human CD163 antigen,CD163 LISA kit |
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201-12-0247 | Shanghai Sunred Biological Technology | 96 tests | EUR 528 |
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
human CD163 antigen,CD163 ELISA kit |
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YLA0098HU-48T | Shanghai YL Biotech | 48T | Ask for price |
human CD163 antigen,CD163 ELISA kit |
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YLA0098HU-96T | Shanghai YL Biotech | 96T | Ask for price |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3460 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1750 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-96StripWells | MyBiosource | 96-Strip-Wells | EUR 425 |
Human CD163 Antigen, CD163 GENLISA ELISA |
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KBH0246 | Krishgen | 1 x 96 wells | EUR 286 |
Mouse Anti Human Cd163 Monoclonal Antibody |
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CABT-47162MH | Creative Diagnostics | 25 µg | EUR 446.4 |
Mouse Anti Human Cd163 Monoclonal Antibody |
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CABT-47163MH | Creative Diagnostics | 0.2 mg | EUR 1057.2 |
Mouse Anti Human CD163, APC Conjugated mAb |
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MBS9431893-100Tests | MyBiosource | 100Tests | EUR 520 |
Mouse Anti Human CD163, APC Conjugated mAb |
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MBS9431893-25Tests | MyBiosource | 25Tests | EUR 275 |
Mouse Anti Human CD163, APC Conjugated mAb |
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MBS9431893-5x100Tests | MyBiosource | 5x100Tests | EUR 2195 |
CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 2 |
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SC308167 | Origene Technologies GmbH | 10 µg | Ask for price |
CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 1 |
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SC117495 | Origene Technologies GmbH | 10 µg | Ask for price |
PE anti-human CD163 |
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E16FHP163-025 | EnoGene | 25 tests | EUR 433.33 |
Description: Available in various conjugation types. |
PE anti-human CD163 |
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E16FHP163-100 | EnoGene | 100 tests | EUR 953.33 |
Description: Available in various conjugation types. |
Anti-Human CD163 PE |
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MBS696987-100Tests | MyBiosource | 100Tests | EUR 415 |
Anti-Human CD163 PE |
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MBS696987-25Tests | MyBiosource | 25Tests | EUR 225 |
Anti-Human CD163 PE |
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MBS696987-5x100Tests | MyBiosource | 5x100Tests | EUR 1820 |
Anti-Human CD163 Antibody |
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101-M291 | ReliaTech | 100 µg | EUR 399 |
Description: CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes. |
APC anti-human CD163 |
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E16FHA163-025 | EnoGene | 25 tests | EUR 520 |
Description: Available in various conjugation types. |
APC anti-human CD163 |
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E16FHA163-100 | EnoGene | 100 tests | EUR 1191.67 |
Description: Available in various conjugation types. |
Anti-Human CD163 APC |
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MBS696989-100Tests | MyBiosource | 100Tests | EUR 480 |
Anti-Human CD163 APC |
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MBS696989-25Tests | MyBiosource | 25Tests | EUR 245 |
Anti-Human CD163 APC |
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MBS696989-5x100Tests | MyBiosource | 5x100Tests | EUR 2115 |
APC anti-human CD163 |
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MBS9459445-100Tests | MyBiosource | 100Tests | EUR 655 |
APC anti-human CD163 |
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MBS9459445-25Tests | MyBiosource | 25Tests | EUR 355 |
APC anti-human CD163 |
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MBS9459445-5x100Tests | MyBiosource | 5x100Tests | EUR 2790 |
FITC anti-human CD163 |
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E16FHF163-025 | EnoGene | 25 tests | EUR 520 |
Description: Available in various conjugation types. |
FITC anti-human CD163 |
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E16FHF163-100 | EnoGene | 100 tests | EUR 1191.67 |
Description: Available in various conjugation types. |
Biotin anti-human CD163 |
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E16FHB163-025U | EnoGene | 25 μg | EUR 346.67 |
Description: Available in various conjugation types. |
Biotin anti-human CD163 |
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E16FHB163-100U | EnoGene | 100 μg | EUR 780 |
Description: Available in various conjugation types. |
Purified anti-human CD163 |
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E16FHU163-100U | EnoGene | 100 μg | EUR 433.33 |
Description: Available in various conjugation types. |
CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 2 |
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RG212754 | Origene Technologies GmbH | 10 µg | Ask for price |
CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 1 |
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RG208557 | Origene Technologies GmbH | 10 µg | Ask for price |
Rabbit Anti Human CD163 Monoclonal Clone ABCC-3 |
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IRBAHUCD163ABCC3C100UL | Innovative research | each | EUR 496 |
Description: Rabbit Anti Human CD163 Monoclonal Clone ABCC-3 |
Recombinant Human CD163/CD163 Protein, His Tag |
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E40KMH346 | EnoGene | 20ug | EUR 495 |
CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 1 |
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RC208557 | Origene Technologies GmbH | 10 µg | Ask for price |
CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 2 |
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RC212754 | Origene Technologies GmbH | 10 µg | Ask for price |
Human CD163 Protein |
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E40KMPH6242 | EnoGene | 20ug | EUR 495 |
Recombinant Human CD163 |
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MBS147285-0001mg | MyBiosource | 0.001mg | EUR 240 |
Recombinant Human CD163 |
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MBS147285-0005mg | MyBiosource | 0.005mg | EUR 310 |
Recombinant Human CD163 |
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MBS147285-005mg | MyBiosource | 0.05mg | EUR 1360 |
Recombinant Human CD163 |
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MBS147285-5x005mg | MyBiosource | 5x0.05mg | EUR 5800 |
CD163 siRNA (Human) |
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MBS8229683-15nmol | MyBiosource | 15nmol | EUR 405 |
CD163 siRNA (Human) |
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MBS8229683-30nmol | MyBiosource | 30nmol | EUR 565 |
CD163 siRNA (Human) |
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MBS8229683-5x30nmol | MyBiosource | 5x30nmol | EUR 2450 |
Anti-Human CD163 Antibody (M130) |
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MBS1564482-01mg | MyBiosource | 0.1mg | EUR 340 |
Anti-Human CD163 Antibody (M130) |
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MBS1564482-5x01mg | MyBiosource | 5x0.1mg | EUR 1235 |
Anti-Human CD163 Antibody (AB101) |
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MBS1570008-01mg | MyBiosource | 0.1mg | EUR 405 |
Anti-Human CD163 Antibody (AB101) |
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MBS1570008-5x01mg | MyBiosource | 5x0.1mg | EUR 1520 |
PE-Cy7 anti-human CD163 |
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E16FHN163-025 | EnoGene | 25 tests | EUR 650 |
Description: Available in various conjugation types. |
PE-Cy7 anti-human CD163 |
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E16FHN163-100 | EnoGene | 100 tests | EUR 1408.33 |
Description: Available in various conjugation types. |
APC-Cy7 anti-human CD163 |
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E16FHO163-025 | EnoGene | 25 tests | EUR 650 |
Description: Available in various conjugation types. |
APC-Cy7 anti-human CD163 |
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E16FHO163-100 | EnoGene | 100 tests | EUR 1408.33 |
Description: Available in various conjugation types. |
PerCP-Cy5.5 anti-human CD163 |
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E16FHS163-025 | EnoGene | 25 tests | EUR 541.67 |
Description: Available in various conjugation types. |
PerCP-Cy5.5 anti-human CD163 |
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E16FHS163-100 | EnoGene | 100 tests | EUR 1278.33 |
Description: Available in various conjugation types. |
Anti-Human CD163 PE-Cyanine7 |
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MBS696988-100Tests | MyBiosource | 100Tests | EUR 505 |
Anti-Human CD163 PE-Cyanine7 |
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MBS696988-25Tests | MyBiosource | 25Tests | EUR 270 |
Anti-Human CD163 PE-Cyanine7 |
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MBS696988-5x100Tests | MyBiosource | 5x100Tests | EUR 2220 |
Mouse Monoclonal anti-human CD163 |
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hAP-0161 | Angio Proteomie | 100ug | EUR 250 |
Mouse Monoclonal anti-human CD163 |
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hAP-0161A | Angio Proteomie | 50ug | EUR 400 |